As we age, visible changes such as facial volume loss, skin sagging, and deepening lines may become more apparent. These are often related to the gradual decline in collagen, a structural protein that helps keep skin firm and youthful-looking. While moisturisers and other skincare products can help improve the skin’s surface, some individuals may consider clinically administered treatments to address deeper structural changes.
One option available in medical aesthetics is a poly-L-lactic acid (PLLA) collagen biostimulator, an injectable treatment designed to gradually encourage collagen regeneration. This treatment does not offer instant volume but works by stimulating the skin’s natural processes over time.
This guide covers everything you need to know about this treatment, including how Collagen Injectables works, the areas it targets, and the results you can expect. You’ll also find practical insights into the treatment process and key factors to consider before deciding if it’s right for you.
The Science Behind Collagen Biostimulator Treatment
The active compound, poly-L-lactic acid, is a biodegradable substance that has been used in medical applications for decades. When injected into specific areas, PLLA particles are absorbed by the body and may help stimulate collagen production. Over a series of sessions, this gradual process may lead to improved facial fullness and skin texture.
This treatment is usually performed by a licensed medical professional and tailored to each patient’s individual concerns. Areas commonly addressed include the cheeks, temples, jawline, and areas with skin creases.
Collagen Stimulation and Regeneration
- The Role of Collagen: Collagen is a key protein responsible for maintaining skin structure, elasticity, and firmness. Ageing reduces collagen production, resulting in wrinkles, volume loss, and skin laxity.
- PLLA Function: PLLA stimulates fibroblasts, encouraging the production of collagen types 1 and 3, as well as elastin. These proteins are vital for maintaining the skin’s integrity and elasticity.
Regenerative Pathway
- Minimising Inflammation: Unlike some treatments that may trigger a pro-inflammatory response, PLLA promotes a regenerative pathway with reduced inflammation, ensuring a supportive environment for tissue renewal.
- Gene Activation: Clinical evidence shows PLLA upregulates genes such as ELN 4 and MMP23, which contribute to collagen and elastin production, enhancing the skin’s structural foundation.
How PLLA Works Differently
- Gradual Results: Improvements appear progressively as collagen production increases, leading to subtle and natural-looking changes.
- Sustainable Effects: Newly generated collagen supports the skin for up to two years or longer with proper care, offering longer-lasting results compared to traditional fillers.
Key Features
- Biocompatible Material: PLLA has a long history of safe use in medical applications.
- Targeted Treatment: Injections are applied to specific areas to stimulate collagen where it is needed most.
- Minimally Invasive: The procedure avoids surgery, making it a convenient option with minimal recovery time.
What to Expect from Your Treatment
Restores Natural Volume
PLLA injectables enhance areas of volume loss, such as the cheeks, temples, and jawline. By activating adipose-derived stem cells (ADSCs) and supporting fat remodeling, the treatment helps renew facial volume while preserving a natural appearance. Clinical evidence reports a 61% improvement in volume in cases of severe facial lipoatrophy within 48 weeks.
Improves Skin Texture and Radiance
The treatment helps stimulate ECM components, including collagen and elastin, to improve skin texture. Over 91% of patients noted sustained improvements in skin radiance, with 86% of practitioners reporting noticeable glow and vitality in treated areas.
Enhances Skin Elasticity and Firmness
The collagen and elastin stimulation from PLLA helps strengthen the skin’s structure, improving elasticity and firmness over time. Nearly 89% of patients reported improved firmness, while over 88% of practitioners observed enhanced jawline contour and skin tightness.
Provides a Lifting Effect
The Collagen Injectable treatment promotes ECM remodeling and ADSC activation, contributing to a natural lifting effect. By strengthening the skin’s foundational layers, it helps combat sagging and achieve a more defined, rejuvenated look.
Reduces Inflammatory Response for Regeneration
The treatment follows a regenerative pathway with minimal inflammation, enabling tissue renewal without triggering adverse reactions. This contrasts with calcium hydroxyapatite-based products, which may elicit a pro-inflammatory response that could diminish regeneration.
Delivers Long-Lasting Results
By regenerating ECM components and supporting the skin’s structural integrity, it achieves results that can last up to two years. Proper care and periodic follow-ups can help maintain these improvements.
Supports Collagen and Elastin Production
It upregulates genes such as ELN 4 and MMP23, which are linked to the production of essential ECM components. This targeted stimulation contributes to long-term benefits in skin quality and resilience.
Is Collagen-Stimulating Injectable Right for You?
Collagen-stimulating injectables work well for individuals who prefer gradual, natural-looking improvements instead of immediate changes. It is a suitable choice for those seeking a minimally invasive treatment with results that develop over time.
Who Can Benefit from This Treatment?
- Individuals experiencing volume loss due to ageing.
- Those who want subtle, progressive enhancements.
- People looking for a treatment option with long-lasting effects.
Who Should Avoid it?
- Individuals with a history of keloid formation or hypertrophic scarring.
- Those with active skin infections in the treatment area.
- Anyone with severe allergies to the treatment ingredients.
NUU Aesthetics & Wellness Clinic offers collagen biostimulators as part of their non-invasive aesthetic treatments. A consultation with a professional is essential to assess your suitability for this treatment and ensure a safe and effective outcome.
FAQs
How long does the Collagen Injectables procedure take?
A treatment session typically lasts between 30 and 45 minutes, depending on the number of areas treated. It is a minimally invasive procedure, making it a convenient choice for individuals with busy schedules.
When will I see results?
Results begin to appear gradually as collagen types 1 and 3, along with elastin, are stimulated. Initial improvements may be noticeable within 4 to 6 weeks after the first session, with full results becoming more evident as the treatment plan progresses. The gradual enhancement ensures a natural-looking outcome.
How many sessions will I need?
Most individuals require 2 to 3 sessions spaced approximately 4 to 6 weeks apart. This schedule allows sufficient time for collagen production and ECM remodeling to develop between treatments. Your practitioner will recommend a personalised plan based on your skin condition and goals.
Is there downtime after treatment?
A collagen injectables treatment involves minimal downtime. Some patients may experience mild redness, swelling, or bruising at the injection sites, which typically resolves within a few days. Most people can resume their normal activities immediately after the procedure.
Are the results permanent?
The collagen injectables are not permanent, but the effects of collagen stimulation and ECM remodeling can last up to two years or longer with proper care. The treatment supports long-term regeneration with minimal inflammatory response, enabling sustained improvements in skin quality and volume. Periodic follow-up treatments may be recommended to maintain the desired outcomes.
Final Thoughts on Collagen Biostimulator Singapore
Collagen-Stimulating Injectable offers a natural and effective way to address ageing concerns without the need for surgery. It works by stimulating your body’s collagen production, helping to restore volume and improve skin texture gradually. This makes it a suitable option for individuals seeking results that develop over time and appear natural.
The Collagen Injectable treatment helps smooth fine lines, enhance elasticity, and provide a refreshed appearance. With minimal downtime, it fits seamlessly into your routine while delivering progressive improvements. Each session builds upon the last, creating a more youthful and balanced look that can last up to two years.
As with any treatment, understanding the pros and cons of this treatment is essential when deciding if it’s the right choice for you. While the gradual improvements and long-lasting effects are significant advantages, the treatment may not be ideal for individuals seeking immediate results. Consulting a qualified provider can help you weigh these factors based on your goals.
In Singapore, poly-L-lactic acid (PLLA) collagen biostimulator is available at NUU Aesthetics & Wellness Clinic, where their team will guide you through the process. With its collagen-stimulating properties, it offers sustainable improvements that enhance your appearance over time. Schedule a consultation to explore whether this treatment aligns with your aesthetic needs.
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